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Advisor-Medicinal Chemistry

San Diego, California

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Req ID R-30100 Title Advisor-Medicinal Chemistry City San Diego State / Province California Country United States Region Research

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our 35,000 employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.

Do you have strong Synthetic Organic or Medicinal Chemistry skills with extensive working knowledge of modern synthetic chemistry methodologies? If you can contribute examples of scientific creativity and ability to ideate independently and in teams solving problems through hypothesis-based experimental design, analysis and integration of complex data sets and mechanism insight, apply today!

The Discovery Chemistry & Technologies organization within Lilly Research Laboratories continues to grow! We seek hardworking scientists to join our Medicinal Chemistry group located at the Lilly Biotechnology Center, San Diego, CA to make an immediate impact. We're looking for scientists with a strong attention to detail, trouble-shooting skills, a high level of learning agility, the willingness to work across teams. We are an innovative and dynamic group looking to enhance our diverse team and capabilities in drug discovery. We are committed to continually improving our abilities to make life better for patients around the globe. Consider joining our growing team!

If you are interested in being considered for employment with a top Pharmaceutical company, please review the following opportunity.

We are looking for someone who can:

  • Keep safety as your top priority at any time, striving to maintain a strong safety culture.
  • Formulate hypothesis, design and synthetize novel small molecules to engage disease modifying targets and contribute decisively to the advancement of drug discovery programs from early lead generation to submission of candidate drugs to the clinic.
  • Leverage world-class structure-based drug design technologies and partner with expert colleagues in computational chemistry and biophysics to characterize protein-ligand interactions and gain key insights supporting de-novo molecular design.
  • Optimize lead compounds to improve potency, selectivity, physicochemical properties and DMPK to meet the desired target product profiles required to invent high-quality medicines.
  • Deliver high laboratory synthetic productivity to inform fast-paced SAR iterations through proposal and execution of synthetic routes.
  • Collaborate with colleagues specialized in high-throughput automated synthesis, route optimization and scale-up to maximize the overall efficiency and productivity of the group.
  • Proactively partner with scientists in areas like pharmacology, translational science, ADME and toxicology to address specific program needs, increase your overall organizational acuity and provide them with Medicinal Chemistry perspectives.

If working for a company where you feel valued and heard is important, apply today and help us improve the lives of patients around the world.

Basic Qualifications:

  • PhD in Organic or Medicinal Chemistry with demonstrated experience in small molecule organic synthesis and synthetic methodology, or MS in Organic or Medicinal Chemistry with >5 years relevant experience.

Additional Skills/Preferences:

  • Strong Synthetic Organic Chemistry skills with deep and extensive working knowledge of modern synthetic chemistry methodologies, experimental work, isolation/purification techniques and structural analysis of synthetic organic molecules. Ability to maintain awareness of latest literature of chemical transformations.
  • Scientific creativity and ability to work independently solving problems through careful experimental design, analysis of complex data sets and mechanistic insight.
  • Robust track record of scientific contributions including peer reviewed publications, patents and presentations.
  • Excellent English language oral and written communication skills, ability to engage highly effectively as team player in a multidisciplinary and international environment.
  • Proficient use of Microsoft Office applications as well as Scifinder, Reaxys or other scientific data tools to identify relevant scientific literature.
  • Strong work ethic. Scientific curiosity. Can do, will do attitude.

Eli Lilly and Company, Lilly USA, LLC and our wholly owned subsidiaries (collectively “Lilly”) are committed to help individuals with disabilities to participate in the workforce and ensure equal opportunity to compete for jobs. If you require an accommodation to submit a resume for positions at Lilly, please email Lilly Human Resources ( ) for further assistance. Please note This email address is intended for use only to request an accommodation as part of the application process. Any other correspondence will not receive a response.

Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.

As a condition of employment with Eli Lilly and Company and its subsidiaries in the United States and Puerto Rico, you must be fully COVID-19 vaccinated and provide proof of vaccination satisfactory to the company (subject to applicable law). 

To submit resume, visit and apply to Req ID R-30100.

Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.

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