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Postdoctoral Scientist FDE - Imaging R&D

Philadelphia, Pennsylvania

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Req ID R-2206 Title Postdoctoral Scientist FDE - Imaging R&D City Philadelphia State / Province Pennsylvania Country United States

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our 39,000 employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.

Position Overview:

Lilly Imaging Research and Development/Avid Radiopharmaceuticals provides technical expertise for molecular imaging to Lilly Research Laboratories. The Postdoctoral Scientist will provide expertise for biological target evaluation for the development of novel PET imaging agents, with a focus on neuroinflammation imaging in neurodegenerative diseases and potentially other disease areas (e.g. auto-immunity). A novel technology taking advantage of spatial resolution has been identified for this project and data generated will have a high impact on existing Lilly programs.  We are looking for a highly motivated postdoctoral fellow with background in neuroscience/neurobiology and morphometry analysis, who will work on identifying novel targets in neuroinflammation.

The Postdoctoral Scientist will be responsible for designing, developing and implementing immuno-histological as well as cellular and biochemical cell profiling experiments. The scientist will be integrated in the Lilly Research Labs Post-Doc community and will benefit from internal cross-functional interactions as well as various training and data sharing opportunities with internal teams and the international scientific community.

Candidates with a strong background and hands-on expertise in neuroscience and neurodegenerative disease research are encouraged to apply.

Responsibilities:

  • Design, develop, and validate tissue-based assays for neurodegenerative disease research
  • Provide strategic and technical expertise on the design and optimization of protein target detection and morphometric quantitative analysis methods
  • Novel imaging target evaluation and validation
  • Ensure good laboratory practice for data documentation
  • Interface with cross-functional colleagues in areas such as Biology, Chemistry, Imaging Analysis and other therapeutic areas from Lilly Research Labs
  • Author scientific publications and present data at international scientific conferences

Basic Qualifications:

  • PhD in Neurobiology or Neuroscience, Immunology, Molecular or Cell Biology, Biochemistry, or related fields required by start of assignment

Additional Skills/Preferences:

  • Proficient in immunohistochemical and biochemical analysis of human derived tissue and knowledge in neuroanatomy and neuropathology
  • Demonstrated excellence in one or more of the following areas: working with brain tissue, cell and molecular biology, immunochemistry, evaluation of small molecules and/or biologicals, imaging analysis modalities, development and validation of screening assays, big data handling
  • Ability to work independently in a fast-paced team environment and with multidisciplinary teams
  • Excellent oral and written communication skills and record of peer-reviewed publications
  • Desire to lead a translational research project
  • Experience with morphometric analysis software and macro development, Prior experience with machine learning is an advantage
  • Hands-on experience with animal models of neurodegeneration/neuroinflammation or immune cells isolation
  • Hands-on experience with single-cell transcriptomics and proteomic datasets
  • Experience in drug discovery of PET molecular imaging agents

Additional Information:

  • 0-10% travel
  • This position is not permanent. It is for a fixed duration of two years with potential to extend to 3 years and for maximum of up to 4 years

About Eli Lilly’s Postdoctoral Scientist Program:

When it comes to research and development, our goal is to discover and deliver innovative medicines that make life better for people around the world. It’s challenging, expensive and often filled with failure. But even when we fail, we advance medical science and understanding by learning more about diseases, biology and chemistry – ultimately bringing new solutions one step closer to reality.

Over the course of our history, we have shed light on some of the toughest health care problems known to man – diabetes, heart disease, infectious diseases, neuroscience disorders, cancer and more. We could not pursue this without our research and development team.

Postdoctoral scientists help us continue this pursuit. During your experience you will get:

  • Top industry research experience
  • Mentoring by some of Lilly’s top scientists 
  • Laboratory and classroom training and education to further your development
  • Collaboration and networking across dozens of postdoctoral scientists and other researchers

Eli Lilly and Company, Lilly USA, LLC and our wholly owned subsidiaries (collectively “Lilly”) are committed to help individuals with disabilities to participate in the workforce and ensure equal opportunity to compete for jobs. If you require an accommodation to submit a resume for positions at Lilly, please email Lilly Human Resources ( Lilly_Recruiting_Compliance@lists.lilly.com ) for further assistance. Please note This email address is intended for use only to request an accommodation as part of the application process. Any other correspondence will not receive a response.

Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.

To submit resume, visit https://www.lilly.com/careers and apply to Req ID R-2206.

Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.

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