At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our 39,000 employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We are looking for people who are determined to make life better for people around the world.
Do you seek an opportunity to lead highly technical drug product development projects while working closely with discovery, clinical, and other development teams? Do you have strong technical problem solving ability and an internal motivation to achieve quality results in a fast-paced environment? If so, we have a role for you!
Small Molecule Design and Development (SMDD) is comprised of diverse groups that design and execute the development of all CMC aspects of small molecules and non-parenteral peptides from pre-clinical phases through commercialization for drug substances and drug products. With a goal of enabling Next Generation Research and Development, we seek to develop and explore new technical solutions across our portfolio. This position will focus on the integration of early clinical and commercialization activities including clinical study and drug product design, formulation development, and global regulatory submission support.
Candidates must leverage a strong background in pharmaceutical sciences, biopharmaceutics, and clinical design to fulfill responsibilities in drug product development which include:
Integrating fundamental pharmaceutical sciences knowledge (formulation, biopharmaceutics, pharmacokinetics) and patient centered aspects into the design of new dosage forms and drug delivery technologies.
Incorporating knowledge of disease state, therapeutic area, and molecular properties to enable drug delivery for novel or difficult to access targets.
Partnering with and influencing groups at the discovery/development/ clinical interface to solve complex technical problems and to identify and implement novel formulations and clinical study designs that maximize benefit to our patients and value to Lilly.
Leveraging exceptional learning agility to apply biopharmaceutics knowledge to delivery of new therapeutic modalities such as oral peptides and oligonucleotides.
Embracing diverse thoughts, backgrounds, and experiences to deliver innovative pharmaceutics solutions that will allow the company to realize its vision of Next Generation Research.
Influencing and engaging the external scientific community to foster collaborations for new drug delivery initiatives and to advance Lilly’s internal portfolio.
Ph.D. in pharmaceutical sciences, biopharmaceutics, PK/PD or related disciplines.
Deep understanding of biopharmaceutics/pharmacokinetic principles, and drug product/process design factors impacting in vivo performance of drug products.
Fundamental understanding of material science and impact on drug product performance and manufacturing.
Knowledgeable and experienced in clinical study design.
Knowledgeable in drug delivery options/systems in particular for new therapeutic modalities (e.g. peptides and oligonucleotides).
Basic understanding of regulatory aspects pertaining to development and clinical testing of drug products.
Limited travel may be required
Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.