At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our 39,000 employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.
Lilly’s Small Molecule Design and Development (SMDD) is involved in key activities for the development of synthetic active pharmaceutical ingredients from pre-clinical phases through commercialization of drug substances and drug products. Our scientists develop key technical and business solutions across the portfolio using their deep technical expertise to speed up testing of the clinical hypothesis and overall drug development. SMDD tackles this diversity of responsibilities by recognizing that an even greater diversity of talents and cultures is necessary to deliver the next generation of life changing medicines to patients.
SMDD is seeking outstanding engineering candidates to work within the process design and development team. The position presents an opportunity to work side by side with chemists, analytical chemists, formulation scientists and modelers to develop new technical solutions to accelerate our portfolio. The position will be based in Indianapolis where research is conducted in a new, state of the art development facility. Candidates must demonstrate a history of strong technical depth, scientific leadership and a willingness to promote a collaborative, team-based approach to problem solving.
The responsibilities and opportunities for this role include:
Apply chemical engineering fundamentals towards designing and optimizing drug substance/drug product processes.
Design and develop novel platforms and control systems to speed up the development of synthetic molecules including small molecules, synthetic oligonucleotides and peptides.
Serve as a member of integrated commercial teams responsible for the development and demonstration of new processes.
Design and execute experiments in a laboratory setting and/or mathematical models to develop robust processes capable of meeting early and late phase demands.
Develop the external manufacturing network, oversee activities and install key capabilities within contract manufacturing organizations (CMOs)
Communicate appropriately to other functions to enable fast commercialization of drugs and to management team to enable sound business decisions.
Engage in a highly collaborative work environment across and beyond SMDD and Lilly, including external academic researchers and pre-competitive collaborations.
Direct and mentor less experienced scientists and engineers to deliver the portfolio and innovation projects.
Publish and present original research externally, author internal technical documents and develop and document control strategies for new product registration applications (manufacturing process and development history portions).
PhD in Chemical Engineering or related discipline
Experience with design, development, control and optimization of unit operations
Experience with modeling and simulation tools, data analytics and predictive analytics.
Experience with online and offline analytical techniques and process analytical technologies (PAT).
Excellent oral communication and documentation skills.
Demonstrated ability to effectively collaborate with multidisciplinary teams
Lilly is an EEO/Affirmative Action Employer, and does not discriminate on the basis of race, gender, protected veteran status, disability or any other legally protected status.