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Research Scientist-Neuropathology

Cambridge, Massachusetts

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Eli Lilly and Company, Lilly USA, LLC and our wholly owned subsidiaries (collectively “Lilly”) are committed to help with individuals with disabilities participate in the workforce and ensure equal opportunity to compete for jobs. If you are an individual with a disability and require a reasonable accommodation to participate in the application process for positions at Lilly please email Lilly Recruiting Compliance for further assistance. Please note, this email address is intended for use only to request an accommodation as a part of the application process. Any other correspondence will not receive a response.

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Req ID 54589 Title Research Scientist-Neuropathology City Cambridge State / Province Massachusetts Country United States Region North America

Company Overview

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our 39,000 employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world. #WeAreLilly


Lilly is passionate about the discovery, development and commercialization of potential new medicines that will impact and improve the lives of patients. Our Neuroscience Next Generation Therapeutics team is an innovation-focused organization striving to identify, develop and apply the most cutting-edge technologies to deliver maximum benefit to our patients. Are you looking to be part of a growing, driven team where you will help to progress new therapeutic approaches toward clinical development and commercialization? Oligonucleotide-based therapies and other novel modalities represent an existing avenue of research toward development of the next generation of therapies.

The Next Generation Therapeutics group is a newly formed team with a focus on using novel therapeutic modalities to deliver medicines for chronic pain and neuro degenerative disorders. The group, based at our Cambridge Innovation Center in Kendall Square, will work with internal and external partners to identify and deliver new novel therapies into patients at speed. The team is seeking experienced and inspiring scientists to join our fast-paced, interdisciplinary team as we leverage innovative RNA/oligonucleotide/gene and genomic based therapeutic agent to enhance our portfolio.

Key Objectives/Deliverables:

  • Contribute to the development of complex IHC/histology/RNAscope based assays
  • Characterize antibodies, conduct reagent evaluation and perform reagent qualification/tissue preparation optimization assessments
  • Troubleshoot technical challenges and provide scientific and technical input to project teams
  • Liaise with statistics and bioinformaticians to ensure optimum design of experiments
  • Work within collaborations with external partners, academic institutions, CROs and consultants as required.
  • Maintain an awareness of new / emerging techniques and tools relevant to the field.
  • Design, execute experiments and perform data analysis, crafting documents and presentations independently, advancing scientific understanding.
  • Provide conceptual guidance into experimental design, integrated data analysis and communication of results to scientific teams and management
  • Generate novel target ideas and contribute to their validation.
  • Identify, procure and implement new automated equipment acquired for new state of the art pathology lab.
  • Recruit, coach, mentor and actively grow our Neuropathology team

Basic Qualifications

  • PhD degree in neuroscience or related scientific field

Additional Skills/Preferences

  • Proven track record in delivering neuropathology-based outcomes
  • Hands-on experience of histology, immunohistochemistry and in situ hybridization, including light microscopy & fluorescence microscopy, multiplexed formats, experience with image analysis software
  • Knowledge of relevant software packages: Halo, VisioPharm, Definiens etc.
  • Ability to adapt and exercise flexibility for changing platform needs, workflows and projects.
  • Excellent communication skills and efficiency in collaborating across functional boundaries.
  • Demonstrated experience in processing, organizing, analyzing and visualizing complex data and information from disparate sources and ability to extract insight from data
  • Ability to multi-task and work in a fast-paced working environment
  • Excellent interpersonal skills and a phenomenal teammate.
  • Ensure compliance with all health and safety regulations
  • Previous experience with oligonucleotide drug discovery is strongly preferred.

Additional Information

Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.

To submit resume, visit and apply to Req ID 54589.

Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.

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