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Research Scientist - Chemo - Informatician

Alcobendas, Spain

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Req ID R-28848 Title Research Scientist - Chemo - Informatician City Alcobendas State / Province Madrid Country Spain Region Research

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our 35,000 employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.

Responsibilities 

The Discovery Chemistry Research and Technologies (DCRT) organization within Lilly Research Labs is a small molecule drug discovery organization with responsibilities spanning from target identification to candidate selection for clinical studies. We are looking to grow our diverse team of scientists. The Computational Chemistry and Cheminformatics (C3) group in DCRT is seeking an experienced cheminformatics scientist to contribute to the application, evolution, and transformation of the Eli Lilly DNA-encoded library (DEL) platform. 

Some key responsibilities: 

  • Contribute strategically to the application, evolution, and transformation of the DEL platform. 

  • Contribute to overall hit finding strategy, leveraging both wet-lab and computational screening technologies. 

  • Work closely with project teams across the portfolio to drive broad application of DEL and delivery of actionable hits in a timely manner. 

  • Development and / or incorporation of scientific software to perform large scale cheminformatics tasks such as library design, predictive modeling, building block selection, reaction informatics and data analysis related to the DEL platform. 

  • Evolve the DEL collection based on Lilly’s target portfolio. 

  • Develop meaningful metrics to evaluate the performance of the DEL platform. 

  • Evolve visualization and noise reducing methods for effective hit identification, validation, and expansion. 

  • Contribute to the selection, establishment, and management of partnerships with external DEL-related technology or service providers, especially in cheminformatics, data management and data analysis aspects. 

  • Act as the liaison between the DEL team and the broader DCRT team and therapeutic areas. 

 

Basic Qualifications 

  • Ph.D. in Computer Science, Cheminformatics, Computational Chemistry, Bioinformatics or related field and 8+ years’ experience within biotech or pharma industrial environment. 

  • Demonstrated contributions to DEL platform development, including library design, informatics workflow and data analytics. 

  • Demonstrated contributions in hit finding for therapeutic projects through the application of DEL. 

 

Additional Skills/Preferences 

  • Experience leveraging artificial intelligence/machine learning (AI/ML) and/or data analytics for applications in DEL and/or virtual library design. 

  • Project-level focus and ability to influence cross functionally. 

  • Experience in Python scripting. 

  • Strong oral and written communication skills, organizational and leadership capabilities. 

  • Experience mentoring and teaching other computational scientists. 

Eli Lilly and Company, Lilly USA, LLC and our wholly owned subsidiaries (collectively “Lilly”) are committed to help individuals with disabilities to participate in the workforce and ensure equal opportunity to compete for jobs. If you require an accommodation to submit a resume for positions at Lilly, please email Lilly Human Resources ( Lilly_Recruiting_Compliance@lists.lilly.com ) for further assistance. Please note This email address is intended for use only to request an accommodation as part of the application process. Any other correspondence will not receive a response.

Lilly does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.

To submit resume, visit https://www.lilly.com/careers and apply to Req ID R-28848.

Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.

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